37 of the most retweeted and funniest Tweets of all time
Twitter is a great medium for sharing nuggets of knowledge, pictures of cats and sage life advice.
Over the years it’s also been a source of entertainment for the internet, even documenting important events as they happen. We’ve seen highs and lows, the good times and the bad.
Here we take you on a journey through the funniest, the most retweeted and most inspiring tweets we’ve seen over the years.
Carter’s nuggets
HELP ME PLEASE. A MAN NEEDS HIS NUGGS pic.twitter.com/4SrfHmEMo3
— Carter Wilkerson (@carterjwm) 6 April 2017
Top of the list is the World record-breaking plea from Carter Wilkerson to Wendy’s food chain for a year’s supply of nuggets that exploded on Twitter this spring and is probably the best example of free advertising ever seen on the social network.
Ellen’s Oscars selfie
If only Bradley’s arm was longer. Best photo ever. #oscars pic.twitter.com/C9U5NOtGap
— Ellen DeGeneres (@TheEllenShow) 3 March 2014
In second place is the previous retweet champion, now knocked off the top spot by #NuggsForCarter. However, it remains the most famous selfie on the web. Shared by Ellen DeGeneres, the tweet likely shows the most celebrities you’re ever likely to see in a single selfie snap.
Ed Balls creates an anniversary
Ed Balls
— Ed Balls (@edballs) 28 April 2011
In 2011, British politician and ex-shadow chancellor Ed Balls made a simple narcissistic Twitter gaffe that became so popular and famous that us Brits turned it into a yearly tradition known as “Ed Balls day”.
The Delta airlines prank
We got kicked out of a @Delta airplane because I spoke Arabic to my mom on the phone and with my friend slim… WTFFFFFFFF please spread pic.twitter.com/P5dQCE0qos
— Adam Saleh (@omgAdamSaleh) 21 December 2016
This tweet apparently showed a man getting kicked off an aeroplane for simply speaking in Arabic on the phone to his mother. The tweet went viral, but was later to revealed to be fake when it was discovered that this tweeter was actually an internet prankster.
United Airlines blunder
United Airlines is pleased to announce new seating on all domestic flights- in addition to United First and Economy Plus we introduce…. pic.twitter.com/KQjPClU2d2
— McNeil (@Reflog_18) 10 April 2017
In April 2017 a man was forcibly removed from a United Airlines flight after he refused to give up his seat. A PR nightmare followed for United Airlines which tried and failed to handle the situation successfully. There were numerous amusing tweets around the incident and the follow-up.
Obama’s last message as President
Thank you for everything. My last ask is the same as my first. I’m asking you to believe—not in my ability to create change, but in yours.
— President Obama (@POTUS44) 11 January 2017
Barack Obama had many popular tweets during his time as President, but his parting words proved to be one of the highest performing tweets on our list.
Obama celebrating more years
Four more years. pic.twitter.com/bAJE6Vom
— Barack Obama (@BarackObama) 7 November 2012
The people of Twitter were pleased to see Obama serving four more years and they showed their love with over 900,000 retweets and more than half a million faves.
One Direction love
Always in my heart @Harry_Styles . Yours sincerely, Louis
— Louis Tomlinson (@Louis_Tomlinson) 2 October 2011
Some tweets do not require explanation.
Kanye West’s creativity ruined
@kanyewest
Kanye West has a bit of a reputation for eccentric tweeting. In one Twitter session, he went on a bit of a tirade after misunderstanding tweets from another rapper that he assumed were about him. The resulting tweets got a lot of Twitter love, but this was the firm favourite.
Lemonade
LIMONADA ????
— elrubius (@Rubiu5) 20 August 2016
One of the most retweeted posts of 2016 came in the form of one word – the Spanish for lemonade. The Youtuber behind the tweet managed to manipulate the numbers by offering prizes to those who retweeted him.
Generous Celebrities
Ok I’ll pay it. Send info https://t.co/xNpkMOSfEt
— NICKI MINAJ (@NICKIMINAJ) 7 May 2017
This tweet doesn’t make the list because of the number of retweets it garnered, but instead due to the act of human decency behind it. Nicki Minaj spent just under an hour on Twitter handing out gifts of money to down-on-their-luck fans. She helped pay for student loans, debts and tuition fees after asking for proof that the requests were legitimate.
Twitter’s co-founder
just setting up my twttr
— jack (@jack) 21 March 2006
Unsurprisingly, one of the most retweeted posts of all time also represents one of the milestones of Twitter’s history with the company’s co-founder Jack Dorsey setting up his own account way back in 2006.
Taylor Swift’s grumpy cat
apologizing to a very needy cat for being gone so long.
— Taylor Swift (@taylorswift13) 6 December 2008
In our next tweet, Taylor Swift shows us that even celebrities suffer from first world problems, especially when they’re cat owners.
The CIA joins Twitter
We can neither confirm nor deny that this is our first tweet.
— CIA (@CIA) 6 June 2014
With their first tweet, the Central Intelligence Agency demonstrated that even spooks can have a sense of humour. The people of Twitter approved of the message with over 300,000 retweets.
Wise last words
A life is like a garden. Perfect moments can be had, but not preserved, except in memory. LLAP
— Leonard Nimoy (@TheRealNimoy) February 23, 2015
Actor, Leonard Nimoy’s last tweet before he died was a poignant yet wise message which struck a chord with fans across the world and resulted in 270,000 retweets.
Channel 4 and Game of Thrones collide
You know nothing, Jon Snow. pic.twitter.com/zBGto7bKaK
— Ryan Nelson (@RyanJohnNelson) December 9, 2014
Hilarity ensues as @RyanJohnNelson picks up on the accidental collision between Jon Snow Channel 4 newscaster and the famous line from Game of Thrones. Only a couple of thousand retweets, doesn’t seem like enough in our opinion. Perhaps someone was hiding the door on this going viral.
Receptionist dog
Sir, sir, if you con, SIR IF CONTUNUE TO RAISE YOUR VOICE I’M GOING TO HAVE TO ASK YOU TO LEAVE SIR. pic.twitter.com/WIuyCntgBg
— Shabba Da Hutt (@Jehwauhn) November 21, 2014
Cats aren’t the only animals that can tickle your funny bone. Dogs can be hilarious too and dogs acting like people, even more so.
Pizza problems
Yoooo I ordered a Pizza & Came with no Toppings on it or anything, Its Just Bread???? @dominos
— ㅤㅤ (@SadderDre) September 1, 2014
In a hilarious pizza faux pas, @SadderDre publicly messaged Dominos to tell them they’d just sent him the dough rather than the pizza he was expecting.
It quickly turned out that the customer is not always right, when this tweeter followed up to say that actually, he’d just opened the box upside down. We’re not even sure how you’d do that, but it was certainly pretty amusing.
Not an actual cloud
Daily Mail tells readers the #iCloud isn’t an actual cloud in the sky pic.twitter.com/hgrYBjMTie
— Ben Black (@BenBlack) September 3, 2014
The readers of the Daily Mail have a certain reputation on the internet, but usually for their comments. Here, a tweeter catches the newspaper dumbing down the technology of the internet for its readers.
Taking Henry for a walk
Once you’ve seen a guy walking his pet Hoover, there is really nothing left to see. pic.twitter.com/JvAf83FNXu
— Michael Clarke (@Mr_Mike_Clarke) December 5, 2014
Certainly easier to look after than a dog, Henry the Hoover even cleans up more mess than he makes. Plus walking him in public makes for hilarious tweets.
Mistakes gone to print
“You’re sure that’s the right word?””Like, 80% sure, yeah.””Print it.” pic.twitter.com/RyteF8V2ko
— carltonhimself (@carltonhimself) June 9, 2015
We’ve seen far more cringeworthy errors going to print over the years, but this pitcher for the Boston Red Sox apparently has many talents including the ability to throw a ball with both hands and to live underwater as easily as he lives on land.
Creative marketing artwork
Incredible way of making my two star review seem like I didn’t hate the film pic.twitter.com/zvOyIxHQ3h
— Benjamin Lee (@benfraserlee) September 8, 2015
In a feat of creative marketing, this poster for the film “Legend”, starring Tom Hardy as both Kray twins, was designed to neatly hide the two-star review from The Guardian. Even the writer of the review was impressed with the craftsmanship.
Minion body wash problems
Slightly disturbing design flaw in this Minion body wash pic.twitter.com/Hko0AMFK9X
— Ash Warner (@AlsBoy) August 23, 2015
This poor Minion probably needs a nice relaxing bath after apparently bleeding from the eyes. Heaven knows what he saw. Probably just a bit of a design flaw spotted by Ash Warner and shared for all to enjoy, rather than the birth of the Anti-Christ.
Pigeon job interview
You’ve seen nothing until you’ve seen a picture of a pigeon having a job interview to become a pigeon: pic.twitter.com/gfkUGVcb3p
— Periwinkle Jones (@peachesanscream) December 18, 2013
Pigeons are generally a menace to modern society, but at least every now and then they can give us some mild amusement. Periwinkle Jones managed to capture this classic moment when one pigeon was caught apparently being given a job interview in the local fast food establishment.
Google’s Teenage birthday
It’s Google’s 15th birthday today. Typical fifteen year old. It’s got an answer for everything.
— Chris (@ChribHibble) September 27, 2013
There’s no denying Chris is right, but what makes it worse is Google not only has an answer for everything, but it’s usually right too.
Ed Sheeran loves ketchup
It upsets me when restaurants think they are too good for ketchup. No one is too good for ketchup. Ketchup is too good for you.
— Ed Sheeran (@edsheeran) September 16, 2013
Ed Sheeran’s tweets are as popular as his songs. He’s a man of the people, with simple tastes – including a fondness for the red sauce.
Low carb diets
I suspect that low-carb diets work not because they are healthier, but because without carbs I simply lose the will to eat.
— Anna Kendrick (@AnnaKendrick47) November 5, 2015
Actress Anna Kendrick has some interesting thoughts on why low-carb diets work and there certainly is no denying her logic.
Ryan Reynolds hilarity
I’d walk through fire for my daughter. Well not FIRE, because it’s dangerous. But a super humid room. But not too humid, because my hair.
— Ryan Reynolds (@VancityReynolds) September 11, 2015
Ryan Reynolds has a reputation for amusing Twitter antics and it’s pretty hard to pick a favourite. However, he’s also shown himself to have some pretty smashing parenting advice under his hat and he really loves his daughter.
Avocados are evil
Avocado: not ripeAvocado: not ripeAvocado: not ripeAvocado: I’M RIPE NOWAvocado: okay you were in the bathroom so I rotted
— Elspeth (@elspetheastman) September 18, 2016
Avocados have a bit of a negative reputation and not without good reason. They might be a superfood, but they’re also sassy with it, tormenting us with the lack of ripeness. Elspeth captured this frustration perfectly in a tweet that 35,000 other people happily agreed with.
Life is going well
friend: how are things?me: things are good!narrator: things were not good
— keely flaherty (@flahertykeely) August 25, 2016
If your life had a narrator, what would they say?
Long-term tweet
I see you shiver with antici …
— Frank Furter (@DrFNFurter) 8 May 2009
… pation.
— Frank Furter (@DrFNFurter) 8 May 2014
You’ve got to tip your hat to this tweeter. Waiting five whole years to deliver a punchline takes some dedication.
Dad jokes
Son: “Mom, Dad.. I’m gay”Mom: *staring at dadDad: …*clenches fists Mom: …don’t!Dad: *sweats profuselyMom:Dad: HI GAY, IM DAD
— Guy Dangerous (@Lerky) 24 October 2015
Dad jokes are the best aren’t they? We were wondering where this one was going for a moment, but we weren’t disappointed.
The taxidermist
date: So what do you do?me: *pulls out stuffed fox* I’m a taxidermistdate: Oh wowfox: and a ventriloquist
— dan mentos (@DanMentos) 28 April 2015
Probably the best taxidermist joke you’ve seen today. Or ever for that matter.
Clickbait
What do we want? CLICKBAITWhen do we want it? The answer will shock you.
— Andy Vale (@AndyVale) 26 August 2015
Clickbait is unfortunately still a thing, but that doesn’t mean we can’t enjoy the fun that this tweet has to offer.
Contemplating life
When parents say to kids “go to ur room & think about what you’ve done” it’s really good practice for what you’ll do every night as an adult
— pat tobin (@tastefactory) 18 September 2015
In a classic “it’s funny because it’s true” tweet, Pat Tobin shares some wisdom about life as we know it.
The DVD prank
4 months ago i quietly left 57 dvds of ‘click’ at my parents’ house and they’ve still never noticed or mentioned it pic.twitter.com/j864rH9eG8
— demi adejuyigbe (@electrolemon) 28 November 2013
This tweet seems like it might have been an expensive prank to carry out with very little results. We’re not even sure we get the joke behind it but 60,000 other people certainly enjoyed it.
Shipwrecked diary
*shipwrecked diary*Day 1: alone, doing well. Mentally sound. Met a crabDay 2: I have married the crab. Day 3: I have eaten my wife.
— brent (@murrman5) 14 August 2013
Living life shipwrecked on a desert island isn’t necessarily all it’s cracked up to be.
The self-aware printer
My neighbor has an unsecured, wireless printer. I just sent this document to it. pic.twitter.com/dBvSmTpfpp
— Shari VanderWerf (@shariv67) 10 July 2013
Sometimes it’s fun to poke at those less technologically capable and if you can turn that into an internet joke, all the better.
Freeview Explore serves up the best daily on-demand content
Freeview Play has a brand new feature that will highlight the best content available on-demand from the BBC, ITV, Channel 4, Channel 5, UKTV Play and any future broadcasters that partner up with the Freeview service.
- What is Freeview Play, when is it coming to my TV and how can I get it?
Appearing as a separate tab in the main Freeview Play menu, Freeview Explore will split content into 10 different genres: Factual, Lifestyle, Movies, Sport, Comedy, Drama & Soaps, Entertainment, Kids, All and a seasonal category such as Christmas or Halloween.
The recommended content that appears in these tabs isn’t determined by your viewing habits, though, something that many other services do. Instead, the content is determined by the broadcasters themselves, so should effectively be able to push more niche content onto your TV, rather than just the big shows that algorithms would say you should like.
A Help & Alerts feature will be rolled out in the coming months too, and this will give users access to instructional videos, news and information on platform updates.
- What Freeview Play TV or set-top box is best for you?
- Humax FVP-4000T review: Freeview Play’s first set-top box
- Why choose Freeview Play? 7 reasons to go free for catch-up
Freeview Explore will roll out on Freeview Play TVs and set-top boxes this month, so keep your eyes peeled for an update.
Samsung HW-MS650 review: A superb single-box soundbar solution
Soundbars are emerging as the preferred choice for a lot of people. Compact, easy to accommodate in the home and getting better and better in performance with every generation, there are plenty of reasons to plump for a smart soundbar over a more traditional sound system.
Companies like Samsung have been investing a lot into audio, resulting in a wide range of diverse speaker offerings, breaking down traditional lines and challenging those brands you might typically associate with premium audio products.
The HW-MS650 slots into the centre of this new world of soundbars. It is smart, connected and stuffed full of innovation. It also sounds superb, getting Samsung off to a great start.
Samsung HW-MS650 review: Design
- 1060 x 78 x 130.5mm; 6.2kg
- Smart mounting solution for Samsung TVs
- Premium build quality
The important thing to note about the MS650 is that it’s a single box solution. There is no separate subwoofer and in many ways that’s part of the appeal, as you don’t have to accommodate a hunk of bass box somewhere in your room. Don’t be fooled into thinking that you’ll be missing out on bass as a result, however, as this soundbar is a bit smarter than that.
The MS650 offers a fairly conventional rectangular design, with neatly chamfered edges to soften the corners. The front is all grille, hiding the nine drivers behind, but also housing a small display on the right-hand side. This display – which can be switched off if you don’t want to see it – conveys basic information, such as the input method, but only shows three characters.
Pocket-lint
On the right-hand end are button controls should you need to manually change anything, such as the input or volume if you don’t have the remote to hand.
There’s no garish branding either, which we really like. That allows the high-quality brushed finish to shine without distraction.
The soundbar is very much designed to be wall mounted, with mounts included in the box, as well as the option to buy a separate WMN300SB mount (£69 from Samsung) that will let you hang the soundbar off the Vesa mount on your TV. If you’re also using Samsung’s “no gap” wall mount, this means fewer holes in your wall and a tidy solution overall.
Samsung HW-MS650 review: Connectivity
- HDMI in and out (ARC), supports 4K HDR
- Digital optical in
- 3.5mm auxiliary input
- Wi-Fi, Bluetooth, Spotify Connect
- Surround sound ready
It’s the MS650’s connectivity that offers a little more than you might elsewhere, specifically when it comes to power. Not only does the soundbar have its own power cable, but you can connect your TV power cable to it too. Well, you can if you’re connecting a Samsung TV and you have the optional cable to let you do this. Doing so will mean you have one less cable draped across your wall. The cable comes with the TV mount mentioned above, so you then have everything for a clean installation.
Pocket-lint
More importantly there is HDMI passthrough, which naturally supports 4K HDR, as well as the conventional optical input, meaning you have a choice of how you connect your devices. HDMI passthrough means you can connect whatever the source of your content is to the soundbar directly and on to the TV. That might be your 4K set-top box (i.e., YouView or Sky Q), although in this world of many devices you’re likely to have more to connect to your TV, meaning you’ll have to rely on the return channel coming to your soundbar.
There’s support for audio return over HDMI, with Dolby Digital and DTS Digital surround decoding, or the included optical connection (cable provided) makes for an easy option with minimal setup, meaning you can simply run the audio from your TV to the soundbar and this will cater for those with older TVs too.
That’s not all the connectivity that the MS650 has to offer either. It also has Wi-Fi to allow an instant connection to your Samsung TV, meaning a wire-free solution if you want it, as well as conventional Bluetooth. With the set being Spotify Connect compatible and Samsung Multiroom compatible (through Wi-Fi again), that means you can simply fire the music from your phone over to play on your soundbar, with outstanding results.
Call us old fashioned, but we prefer the cable connection option for traditional media content, especially when connecting to a recent Samsung TV with a One Connect box, as it’s so simple to run an HDMI cable to the soundbar.
Pocket-lint
There’s one irritation if you do choose to connect to Wi-Fi with your soundbar: we found the MS650 would connect and disconnect from Wi-Fi, even when we were using it for HDMI audio. When it connects you get a message on the display, and the same when it disconnects again. That random and unnecessary repeat notification gets rather irritating when you’re watching a movie.
Samsung HW-MS650 review: Sound and performance
- Virtualised surround sound
- Smart and specific sound modes
- Excellent performance
Let’s get to the heart of the matter. Samsung is calling the MS650 soundbar a Sound+ soundbar. As we said, that means there’s no separate subwoofer, aiming to deliver the bass you need along with the rest of the sound from the same unit.
Pocket-lint
To help make this happen, there are nine speakers in the MS650, split between six woofers and three tweeters. These are grouped into left, right and centre, with each section getting a pair of woofers and a wide-range tweeter. That arrangement means that the soundbar can effectively widen the soundstage, giving you immersive audio from the left and right, while firing out a clear central channel to keep dialogue crisp.
There are nine amplifiers driving these speakers, as well as some very clever technology that cancels bass distortion. This analyses and predicts the distortion that’s likely to occur, meaning tighter control over the woofers so that it can counter distortion for crisp and precise sounding bass response.
The results are fantastic. We’ve become accustomed running a soundbar with a pretty big subwoofer as that’s the most common setup. Often, however, the woofer is a lot more powerful than you need it to be – apart from when you really want to annoy the neighbours. Samsung’s solution is cleaner, meaning less to plug in and accommodate, while also sounding fantastic.
Where that really manifests itself is when the bass kicks in on movie soundtracks; turn the volume up high and the MS650 isn’t marred by dumb bass rumblings, it’s a smarter solution with smarter results.
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You also don’t need to crank up the volume to get the best out of the MS650. At normal listening levels you’ll find a good presentation with that tight bass, clear vocals and a soundscape that’ll keep that movie swimming along.
For those who want to expand the system, the MS650 is also compatible with the SWA-9000S kit, which is a £249 addition that gives you two wireless rear channels. It’s no Atmos experience, however, so if full Atmos surround/projection is what you’re after then look to the HW-K950 Atmos soundbar.
The MS650 also makes a great music system. Thanks to the simplicity of Samsung Multiroom you can very easily pick the source, make pairings with other Samsung speakers and listen to your music without your TV being in the picture, with support for a lot of services.
There are several sound modes that Samsung has packed in too. These can be accessed via a Samsung TV’s controls – at least on the Samsung Q7 and MU7000 that we tested it with – or via the buttons on the remote. The surround option will expand the soundstage somewhat for those more immersive effects with a noticeable left-right spread without totally sucking you in due to the lack of rear channels.
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Surround can be on or off, as can the Smart mode which can give a noticeable lift to some TV programme audio. However, you might just find that with a tweak of volume and bass that the Standard mode will suit you fine. You can switch modes through the included remote, but more detailed controls, including firmware updates, need that Samsung Multiroom app.
Verdict
The aim of Sound+ and of this Samsung soundbar is to give you great audio with no fuss. And it’s mission accomplished. The MS650 is so easy to use as a single box sound solution and it performs so well that it’s impossible not to recommend it. It’s a clean solution with very few compromises.
There’s also a lot more on offer for those who want to expand the system or do more than just make Eastenders sound better. The option for a rear channel, more sophisticated mounting options, or making this part of a multiroom system all add appeal, as do the convenience of things like Spotify Connect.
Ultimately, the MS650 is all about sound quality and convenience. This is a wonderful soundbar with great integrated bass performance. While there are cheaper options on the market, there’s no denying this is a single-box package that delivers in abundance.
The Morning After: Wednesday, June 21st 2017
Hey, good morning!
It’s the middle of the week and we’re discussing the source of those Apple leaks, review the new OnePlus 5, and report on some big changes at Uber.
A powerhouse with a modest price tag.
Review: OnePlus 5

Building a great phone is hard enough, so building a great phone on a budget should be infinitely more difficult. With its fifth flagship, OnePlus makes it look easy. The OnePlus 5 is blazingly fast, with a surprisingly good dual camera and solid battery life. OxygenOS is a refreshingly light take on Android, too, and the phone’s build quality seems top-notch. It’s too bad that OnePlus’ designs seem to be getting more generic as time goes on, and that the phone’s screen doesn’t pack the same punch as its competitors. Ultimately, despite some compromises, the OnePlus is both an excellent phone and an excellent value.
This month: a 1997 sim and an indie rogue-lite.
IRL: What we’re playing in June
E3 might be done and dusted for another year, but every year there are dozens of great games released, all of which are available right now. Fittingly, our picks this month range from a 1997 sim all the way up to a game that was released just today.
Just ask for “jobs near me.”
Google Search will help you find your next job
Say hello to your new recruiter. An update to Google Search on desktop and mobile means you can search for new employment with conversational queries like “jobs near me” and “teaching jobs.” You’ll then see a list of results from across the web, each of which includes the company’s name, the role, the hours and when the job was posted. It’s also got some AI smarts built-in to hopefully ensure a better hiring fit.
179 days to go.Travis Kalanick resigns from his post as Uber CEO

The same day Uber rolled out a way for riders to tip their drivers and promised 180 days of improvements, CEO and co-founder Travis Kalanick succumbed to investor pressure and stepped down. After years of scandals, a letter from a group of prominent investors helped force the executive out, though he still owns a large part of the company and will continue to be a board member. Is that enough to turn the company’s year around? Who knows, but with the company missing a CEO, COO and CFO there aren’t many execs left to take the blame.
Prime Wardrobe is like Stitch Fix but without the stylist or the fee.
Amazon is the latest to offer clothes-by-mail to try on at home

Amazon’s latest service, Prime Wardrobe, is trying to make online clothes shopping a commitment-free experience — one of the few advantages brick-and-mortar stores still had on online retailers. With Prime Wardrobe, you pick out a number of items, including clothes, shoes, and accessories. Then, if you have at least three, Amazon will send them to you and you’ll have a week to try them on and decide what you like. Whatever you don’t want can be sent back for free and you’re only charged for what you keep. If you keep at least three things, you’ll get 10 percent off; and you’ll get 20 percent off if you keep at least five. Buy in bulk: that’s what Amazon is hoping.
Apple’s anti-leaking efforts gets leaked.
Apple tries to clamp down on leaks with mixed success

For the longest time, Apple product leaks tended to come from the supply chain: a factory worker would send parts or a design file to accessory makers eager to get a head start on their next iPhone cases. You might want to rethink that assumption. In a leaked secrecy briefing (!), Apple’s David Rice revealed that leaks from the company’s campuses were more common in 2016 than those from suppliers.
But wait, there’s more…
- The Big Picture: Using a 3D render as a French ID card ‘photo’
- Tesla driver in fatal Autopilot crash ignored safety warnings
- Google can turn an ordinary PC into a deep learning machine
ISS will carry artificial organs in hope of medical breakthrough
In the near future, the International Space Station (ISS) will serve as home to five organs-on-chips research experiments. Each one will tackle a different issue, but all of them are expected to shed light on the effects of microgravity on the human body and could lead to better treatments and drugs without the need for animal testing. Organs-on-chips are transparent slides about the size of an AA battery with microfluidic channels capable of reproducing blood and airflow that are lined with the cells of the organ begin studied. Aboard the ISS, astronauts can observe the cells as they grow in 3D, since the lack of gravity means they don’t settle at the bottom or flatten against the channels’ plastic walls.
The first project wants to find out how microgravity’s negative effect on the immune system triggers respiratory infections, which are a common ailment for ISS crew members. Another one wants to study the effects of medication on mitigating bone and cartilage degeneration, which could benefit those suffering from osteoarthritis and similar conditions. The third one wants to study cellular aging as it happens in zero-G and the cells’ recovery after returning to Earth’s environment.
Another team team will send a kidney-on-a-chip model to the ISS to figure out how microgravity affects kidney function. They intend to use their results to conjure up better treatments for conditions like proteinuria, osteoporosis and kidney stones. The last project’s study will use a brain-on-a-chip model to gather the data needed to optimize the organ-on-a-chip platform itself. While the team’s main goal is to create an automated chip that can make conducting research faster and easier, their results could also provide new insight on neurodegeneration, traumatic injury and cancer.
These five will make their way to the ISS as part of a four-year collaboration between the National Center for Advancing Translational Sciences (NCATS) and the Center for the Advancement of Science in Space. NCATS will provide the projects with two years of initial funding worth approximately $6 million and will continue funding the ones that perform well for another two years after that. Christopher P. Austin, the center’s director, said in a statement:
“The opportunity to partner with CASIS to perform tissue chip science on the International Space Station is a remarkable opportunity to understand disease and improve human health. Physiological functions in the microgravity of the International Space Station will provide insights that will increase translational effectiveness on earth, including identifying novel targets for drug discovery and development.”
Source: CASIS, NASA
Mayor of London wants a zero-emission transport system by 2050
London mayor Sadiq Khan has a wildly ambitious plan to make the English capital more environmentally friendly. In a draft “Transport Strategy,” which is now subject to public consultation, he suggests making London’s entire transport system zero emission by 2050. That deadline, of course, is a long way off, so Khan has outlined some stepping stones too. He wants all taxis and private hire vehicles to be zero emission “capable” by 2033, followed by buses in 2037 and all remaining road vehicles by 2040. “Transport emissions can blight the streets, harming human health and contributing to climate change now and in the future,” he says.
These measures would help the mayor to establish a “zero emission zone” in central London by 2025, ahead of a larger “inner London” territory by 2040 and a city-wide zone by 2050. “London must meet legal pollution limits as soon as possible,” Khan continues. “This requires an earlier introduction and expansion of the Ultra Low Emission Zone and making sure public services lead the way. Air quality and climate change are such pressing issues with such dire consequences that London should provide international leadership.” Strong words, especially when the capital’s population is expected to rise from 8.7 million to 10.5 million by 2041.
Khan has a larger vision, however, that involves the British public ditching automobiles altogether. He wants walking, cycling and public transport to make up 80 percent of London journeys by 2041. That’s up from the current total of 64 percent and equates to 3 million fewer car journeys each day. Such a shift would help the public to lead healthier and greener lifestyles, he says, and reduce instances of heart disease and cancer. To aid that transition, Khan is proposing an expanded network of cycle lanes in the city and refreshed ‘Legible London’ maps for pedestrians.
That’s the carrot — now here’s the stick. The Mayor of London says he would keep the city’s congestion charge “under review” and explore new ways to better penalise motorists in the city. One such method would be “new technology,” developed by Transport for London, that could measure distance, time, emissions and road danger for each journey in the city. A single, per mile charge could then be calculated based on these metrics and how the driver has contributed to overall congestion and pollution. “We have to make not using your car the affordable, safest and most convenient option for Londoners going about their daily lives,” he said.
Other measures include “liveable neighbourhoods” and “healthy routes,” which would provide safe, walkable spaces for citizens. The Transport Strategy also mentions car parking restrictions and expanded, secure cycle parking in all new buildings. It’s a big dream, and one that will no doubt be tweaked and reworked in the coming years. Khan is, after all, highly unlikely to be the Mayor of London in 2050. When someone else takes his place, they’ll likely arrive with new ideas about how the English capital can prosper. If you have any feedback about this particular vision, however, you can submit them as part of the consultation before October 2nd.
Source: Mayor of London
Uber CEO Travis Kalanick Resigns
Uber founder Travis Kalanick has resigned his position as CEO, following a series of controversies and scandals that have recently dogged the ride hailing company.
Five major investors demanded Kalanick’s immediate resignation on Tuesday in a letter delivered to the chief executive, according to The New York Times. After “long discussions” with some of the investors, Kalanick agreed to step down, but will reportedly stay on Uber’s board and continue to hold the majority of voting shares. Kalanick recently took a leave of absence following the death of his mother.
Kalanick at LeWeb Paris (Image by Adam Tinworth)
“I love Uber more than anything in the world and at this difficult moment in my personal life I have accepted the investors request to step aside so that Uber can go back to building rather than be distracted with another fight,” Mr. Kalanick said in a statement.
Uber’s board said in a statement that Kalanick had “always put Uber first” and that his resignation would give the company “room to fully embrace this new chapter in Uber’s history.” An Uber spokesperson declined to comment further.
The ride-hailing service clearly hopes that news of Kalanick’s resignation will be perceived as a company reboot, as it attempts to revive its tarnished image following multiple controversies over recent months.
Just last month it was revealed that the Department of Justice is investigating Uber over its use of “secret” software that allowed its drivers to operate in areas where the company was banned or restricted. The so-called “greyball” software is said to have allowed the company to identify undercover officials and block them from booking rides, in order to prevent them from proving that Uber was operating illegally.
In April it emerged that Apple CEO Tim Cook threatened to pull Uber’s app from the App Store in early 2015 after discovering that it was secretly “fingerprinting” iPhones that used the app. Uber said it used the identification method to prevent fraud, despite knowing the tactic is a clear violation of Apple’s app privacy guidelines. The revelation came in a New York Times article detailing the ride-hailing service’s history of controversial business tactics.
Tag: Uber
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Swift Creator Chris Lattner Quits Tesla After Only Six Months in the Job
Swift creator Chris Lattner, who left Apple to become vice president of Tesla’s autopilot program, has parted ways with the electric car maker after just six months in the job.
“Chris just wasn’t the right fit for Tesla, and we’ve decided to make a change,” Tesla said Tuesday, according to The Wall Street Journal. Lattner followed Tesla’s statement with a post on his Twitter account announcing his interest in available roles for a “seasoned engineering leader”.
The parting of ways will come as a surprise to some observers, given Lattner’s previous standing at Apple and his stated enthusiasm for a new challenge. Back in January, Lattner told MacRumors how much he loved writing code at Apple, and that leaving had been a “very difficult decision” but ultimately he was “ready to move onto something else” and the prospect of working on Tesla’s Autopilot team was “irresistible”.
Turns out that Tesla isn’t a good fit for me after all. I’m interested to hear about interesting roles for a seasoned engineering leader!
— Chris Lattner (@clattner_llvm) 21 June 2017
However, as noted by WSJ, Lattner is just the latest departure in an recent exodus of talent from the program, which has been under increasing pressure from Tesla CEO Elon Musk to develop an autonomous car system, with a company target to demonstrate a car that can drive itself by the end of 2017 inching ever closer.
The program has also faced questions about the safety of the proposed technology, following a fatal crash last year in Florida involving a Tesla equipped with a semiautonomous system, which assists drivers during tasks like steering, braking, and changing lanes.
Lattner’s hiring in January coincided with the departure of Autopilot program director Sterling Anderson. Tesla sued Anderson after he tried to create a competing startup, but the lawsuit was settled in April.
Tag: Tesla
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OnePlus 5 launch: What happened and can I watch it again?
OnePlus has just announced its latest flagship phone. It offers an experience like that of many of today’s flagship smartphones, except – as usual – at a much lower price.
The phone was unveiled via YouTube and Facebook Live in a fairly low key, roughly one hour long announcement. Here’s everything you need to know about what happened.
- OnePlus 5 review: The flagship-killer’s coming of age
- OnePlus 5: Release date, hardware specs and everything else you need to know
- OnePlus 5 vs Apple iPhone 7 vs iPhone 7 Plus: What’s the difference?
When was the OnePlus 5 launch event?
The OnePlus 5 launch event took place at 12pm EST (9am PST/5pm BST) on Tuesday 20 June. It was a pre-recorded announcement streamed live internationally.
In addition, the company will be holding pop-up launch events in many major cities, including London, New York, and Berlin, on 20 June and 21 June. The phone will be shown off to a live audience at each of these events. Check out OnePlus’ website to RSVP your spot.
Can you re-watch the OnePlus 5 event online?
Yes. Here is the OnePlus 5 launch stream, which you can re-watch right here:
What happened at the OnePlus 5 launch?
Unlike most other phone manufacturers, OnePlus only concentrates on building one product at a time. Specifically, this is normally a high-end smartphone that doesn’t cost as much as the competition. This year is no different. Only one device was shown off during the launch event.
The OnePlus 5 is the latest in this lineup and it features Qualcomm’s most powerful processor yet. This 2.45GHz Snapdragon 835 chip is paired with either 6GB or 8GB of RAM. This chipset isn’t just more powerful, it’s also more efficient than before, as is the type of RAM used. This means you get the same (if not better) performance from the 3,300mAh battery than what was delivered by the OnePlus 3T’s 3,400mAh cell.
OnePlus
On the back, there’s a dual camera made up of one 16-megapixel f/1.7 camera and a 20-megapixel f/2.6 camera. These combine to produce background blur on portrait mode photos and also enable a quick 2x zoom without losing much detail. It also has EIS (electronic image stabilisation) to reduce blur when you’re moving and shooting. There’s also a new Pro mode, which includes a horizontal reference line and a histogram.
Like the previous two models, the OnePlus 5 has a 5.5-inch full HD AMOLED display, this time coated in Corning Gorilla Glass 5. Undoubtedly one of its best features, however, is the Dash Charge technology which can deliver enough charge in 30 minutes to get you through a full day.
It’s available in Midnight Black and Slate Gray, with 128GB and 64GB storage respectively. The lower capacity grey model is £449, while the higher spec black model is £499. It’ll be available to buy direct from OnePlus from June 27, and will also be on the high street, through O2’s retail stores.
Lenovo’s pro workstation is as light as a MacBook Air
It’s not just laptops that are getting downsized thanks to next-gen graphics chips and processors. Lenovo has unveiled a new workstation, the P320 Tiny, with a discreet professional GPU and Intel Core i7 chip, all in a box that weighs the same as a MacBook Air (2.9 pounds). Users won’t be suffering for performance, as it features an Intel Core i7-7700T max CPU, NVIDIA Quadro P600 GPU, up to 32GB of DDR4-2400 RAM and 2TB of maximum storage, via a pair of M.2 SSD slots.
While that won’t give you the pure gaming graphics horsepower of an NVIDIA GTX 1080, users will get a pro-level card that has better compatibility with certain 3D and CAD programs. That’s not to mention the attractive storage and memory options that best most laptops.
Despite the tiny size (1.4 x 7.1 x 7.1-inches) the P320 Tiny also has a surprising number of ports, including six USB 3.0, front audio ports, gigabit ethernet and six, count ’em, display ports (four mini-DisplayPort and two DisplayPort).
Some sacrifices must be made for such a tiny device, and in this case, it’s the fact that the power supply is outside the PC in the form of a brick. However, that still frees up space on the desktop, and the relatively low price makes it a prime candidate for FX, 3D and CAD-oriented companies looking for relatively cheap artist workstations.
The P320 Tiny starts at $800, though the top configuration with the Intel i7-7700T CPU, max 32GB of RAM and maxed out M.2 storage is probably at least double that. Lenovo says the product is available now, but I’m not seeing it yet on its US store.
Source: Lenovo



